The main issue that divided Jesus from the Pharisee leaders of Israel was power.
Jesus was performing miracles that the Pharisees had no control over and that they could not perform themselves. Jesus also changed a few of the laws without the Pharisees consent. Divorce was one of the laws that Jesus had changed. He declared that divorce was no longer legal and those who did get divorced and remarried were committing adultery, which was an immense sin to commit.
Jesus would enter into temples to preach and to heal people. Sometimes He even healed people on the Sabbath which was very, very “sinful” in the eyes of the Pharisees. Another thing that bothered the Pharisees was that people claimed that Jesus was the King of the Jews. Pilate, one of the head officials in Israel, asked Jesus if He was the King of the Jews and Jesus replied “It is as you say” in Mark 15:2.
If the Pharisees had just listened to Jesus and had not been so jealous of Him they could’ve had a wonderful relationship together and the Pharisees could’ve learned so much from Him. But Satan is always lurking around waiting to snatch a new victim to exploit; in this case Satan’s victims were the Pharisees.